What type of test can be affected if the sample is not collected in the proper tube?

Coagulation tests are particularly sensitive to the type of tube used for collection due to the additives present in the tubes. These tests often require tubes with sodium citrate as their additive because this anticoagulant is essential for preserving the blood sample in a way that accurately reflects the blood's coagulation properties.

Using the incorrect tube, such as one containing a gel separator or anticoagulants that interfere with coagulation, can lead to inaccurate test results. It may either activate coagulation pathways or interfere with the proper analysis of clotting factors, ultimately impacting patient diagnosis and treatment decisions.

The other tests mentioned do have specific collection requirements as well, but they are generally less sensitive to the type of tube compared to coagulation tests. For example, while serum chemistry tests need to be collected in tubes that allow for serum separation, they might not be as directly impacted by inappropriate tube choice in the same manner as coagulation tests.